Cargando…

miR-539 activates the SAPK/JNK signaling pathway to promote ferropotosis in colorectal cancer by directly targeting TIPE

Colorectal cancer (CRC) is a common tumor that harms human health with a high recurrence rate. It has been reported that the expression of microRNA-539 (miR-539) is low in several types of cancer, including CRC. Tumor necrosis factor (TNF)-α-induced protein 8 (TNFAIP8/TIPE) is highly expressed in CR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yan, Lin, Zeyang, Han, Zhaopu, Wu, Zhengxin, Hua, Jianyu, Zhong, Rui, Zhao, Ruidan, Ran, Honggang, Qu, Kaiyong, Huang, Hongfei, Tang, Huamei, Huang, Jiyi, Liu, Zhongchen, Hong, Xuehui, Peng, Zhihai, Zhuang, Guohong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487425/ https://www.ncbi.nlm.nih.gov/pubmed/34601499 http://dx.doi.org/10.1038/s41420-021-00659-x

Ejemplares similares

Expression of TIPE family members in human colorectal cancer
por: Zhong, Mengya, et al.
Publicado: (2021)

Clinical significance of TIPE expression in gastric carcinoma
por: Hu, Ruyi, et al.
Publicado: (2016)

TIPE-mediated up-regulation of MMP-9 promotes colorectal cancer invasion and metastasis through MKK-3/p38/NF-κB pro-oncogenic signaling pathway
por: Chen, Huiyu, et al.
Publicado: (2020)

Negative Regulation of the Sapk/Jnk Signaling Pathway by Presenilin 1
por: Kim, Jin Woo, et al.
Publicado: (2001)

Identification of Novel Immune Ferropotosis-Related Genes Associated With Clinical and Prognostic Features in Gastric Cancer
por: Xiao, Chen, et al.
Publicado: (2022)

TIPE regulates VEGFR2 expression and promotes angiogenesis in colorectal cancer
por: Zhong, Mengya, et al.
Publicado: (2020)

TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC
por: Zhong, Mengya, et al.
Publicado: (2021)

JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells
por: Neganova, Irina, et al.
Publicado: (2016)

Antidepressant-like effects of Chaihu-Shugan-San via SAPK/JNK signal transduction in rat models of depression
por: Li, Yun-Hui, et al.
Publicado: (2014)

Activation of SAPK/JNK by camptothecin sensitizes androgen-independent prostate cancer cells to Fas-induced apoptosis
por: Costa-Pereira, A P, et al.
Publicado: (2000)

Moscatilin induces apoptosis of pancreatic cancer cells via reactive oxygen species and the JNK/SAPK pathway
por: Zhang, Lei, et al.
Publicado: (2017)

Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway
por: Dulay, Rich Milton, et al.
Publicado: (2021)

αV Integrin Induces Multicellular Radioresistance in Human Nasopharyngeal Carcinoma via Activating SAPK/JNK Pathway
por: Ou, Juanjuan, et al.
Publicado: (2012)

Silibinin induces G1 arrest, apoptosis and JNK/SAPK upregulation in SW1990 human pancreatic cancer cells
por: Zhang, Xiaokai, et al.
Publicado: (2018)

TIPE2 inhibits GC via regulation of cell proliferation, apoptosis and inflammation
por: Lin, Zhenhe, et al.
Publicado: (2018)

Genome-Wide Identification and Characterization of the LpSAPK Family Genes in Perennial Ryegrass Highlight LpSAPK9 as an Active Regulator of Drought Stress
por: Xing, Jing, et al.
Publicado: (2022)

Cis-urocanic acid inhibits SAPK/JNK signaling pathway in UV-B exposed human corneal epithelial cells in vitro
por: Jauhonen, Hanna-Mari, et al.
Publicado: (2011)

(-)-Epigallocatechin Gallate Reduces Platelet-Derived Growth Factor-BB-Stimulated Interleukin-6 Synthesis in Osteoblasts: Suppression of SAPK/JNK
por: Takai, Shinji, et al.
Publicado: (2008)

Effects of Extremely Low Frequency Electromagnetic Fields on Melanogenesis through p-ERK and p-SAPK/JNK Pathways in Human Melanocytes
por: Kim, Yu-Mi, et al.
Publicado: (2017)

Ketamine and Propofol Protect Neuron Cells from Oxygen-Glucose Deprivation-Induced Injury through SAPK/JNK Signalling Pathway
por: Qi, Aihua, et al.
Publicado: (2020)

Protein Interactomic Analysis of SAPKs and ABA-Inducible bZIPs Revealed Key Roles of SAPK10 in Rice Flowering
por: Liu, Xixi, et al.
Publicado: (2019)

Asymmetric dimethylarginine attenuates serum starvation-induced apoptosis via suppression of the Fas (APO-1/CD95)/JNK (SAPK) pathway
por: Li, H, et al.
Publicado: (2013)

Decrease of PKB/Akt Phosphorylation is Partially Mediated by SAPK/JNK Activation in Serum-free L6 Myoblasts Starved with Low Glucose
por: Kim, Mee-Young, et al.
Publicado: (2014)

Activation of the JNK/SAPK and P38 Mitogen-Activated Protein Kinase Signaling Pathways Sensitize Tumor Cells to Cisplatin-Induced Apoptosis
por: Mansouri, Abdel, et al.
Publicado: (2001)

The Drosophila TIPE family member Sigmar interacts with the Ste20-like kinase Misshapen and modulates JNK signaling, cytoskeletal remodeling and autophagy
por: Chittaranjan, Suganthi, et al.
Publicado: (2015)

Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells
por: Wu, Jingjing, et al.
Publicado: (2015)

Flavonoids from Engineered Tomatoes Inhibit Gut Barrier Pro-inflammatory Cytokines and Chemokines, via SAPK/JNK and p38 MAPK Pathways
por: Tomlinson, Matthew L., et al.
Publicado: (2017)

Expression and roles of TIPE2 in autoimmune hepatitis
por: Qian, Jinhua, et al.
Publicado: (2017)

Mapk/Sapk Signaling in Apoptosis and Bfgf-Mediated Survival
por: Schamberger, Chantal, et al.
Publicado: (2001)

AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis
por: Zerp, Shuraila F, et al.
Publicado: (2009)

RITA can induce cell death in p53-defective cells independently of p53 function via activation of JNK/SAPK and p38
por: Weilbacher, A, et al.
Publicado: (2014)

Celecoxib, indomethacin, and ibuprofen prevent 6-hydroxydopamine-induced PC12 cell death through the inhibition of NFκB and SAPK/JNK pathways
por: Ramazani, Elham, et al.
Publicado: (2019)

microRNA-202激活JNK/SAPK信号通路增强多发性骨髓瘤细胞药物敏感性的研究
Publicado: (2016)

Knockdown of TIPE2 increases the proliferation in lipopolysaccharide-stimulated gastric cancer cells
por: Liu, Wenming, et al.
Publicado: (2018)

TIPE2 deletion improves the therapeutic potential of adoptively transferred NK cells
por: Bi, Jiacheng, et al.
Publicado: (2023)

Differential Effects of TipE and a TipE-Homologous Protein on Modulation of Gating Properties of Sodium Channels from Drosophila melanogaster
por: Wang, Lingxin, et al.
Publicado: (2013)

The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation
por: Li, Yan, et al.
Publicado: (2021)

The sucrose non-fermenting-1-related protein kinases SAPK1 and SAPK2 function collaboratively as positive regulators of salt stress tolerance in rice
por: Lou, Dengji, et al.
Publicado: (2018)

SAT539 Thyroid Cancer Presenting as Aspiration Pneumonia
por: Aslam, Sadia, et al.
Publicado: (2023)

Fas Induces Cytoplasmic Apoptotic Responses and Activation of the MKK7-JNK/SAPK and MKK6-p38 Pathways Independent of CPP32-like Proteases
por: Toyoshima, Fumiko, et al.
Publicado: (1997)

Cannot write session to /tmp/vufind_sessions/sess_qkc1t83kqs6mnl4v1t7k3ecl94