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TGF-β-induced PLEK2 promotes metastasis and chemoresistance in oesophageal squamous cell carcinoma by regulating LCN2

Oesophageal squamous cell carcinoma (ESCC) has a relatively unfavourable prognosis due to metastasis and chemoresistance. Our previous research established a comprehensive ESCC database (GSE53625). After analysing data from TCGA database and GSE53625, we found that PLEK2 predicted poor prognosis in...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Zhang, Chaoqi, Cheng, Hong, Liu, Chengming, Lu, Zhiliang, Zheng, Sufei, Wang, Sihui, Sun, Nan, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487427/
https://www.ncbi.nlm.nih.gov/pubmed/34601488
http://dx.doi.org/10.1038/s41419-021-04155-z