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In vivo blockade of 5HT3 receptors in the infralimbic medial prefrontal cortex enhances fear extinction in a rat model of PTSD

OBJECTIVE(S): Treatments that reverse deficits in fear extinction are promising for the management of post-traumatic stress disorder (PTSD). 5-Hydroxytryptamine type 3 (5-HT3) receptor is involved involved in the extinction of fear memories. The present work aims to investigate the role of 5HT3 rece...

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Detalles Bibliográficos
Autores principales: Mohammadi-Farani, Ahmad, Taghadosi, Mahdi, Raziee, Sara, Samimi, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487606/
https://www.ncbi.nlm.nih.gov/pubmed/34630955
http://dx.doi.org/10.22038/ijbms.2021.54299.12197