Synthesis and biological evaluation of novel quinoline analogs of ketoprofen as multidrug resistance protein 2 (MRP2) inhibitors

OBJECTIVE(S): A new series of quinoline analogs of ketoprofen was designed and synthesized as multidrug resistance protein 2 (MRP2) inhibitors using ketoprofen as the lead compounds. MATERIALS AND METHODS: The cytotoxic activity of the compounds was evaluated againt two cancer cell lines including A...

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Detalles Bibliográficos
Autores principales: Mosaffa, Fatemeh, Hadizadeh, Farzin, Fathi, Faezeh, Eslami Nasab, Zahra, Pourzahed, Tahereh, Aboutorabzade, Sayyed Mohammad, Ghodsi, Razieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487607/
https://www.ncbi.nlm.nih.gov/pubmed/34630959
http://dx.doi.org/10.22038/ijbms.2021.54554.12265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487607/
https://www.ncbi.nlm.nih.gov/pubmed/34630959
http://dx.doi.org/10.22038/ijbms.2021.54554.12265

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