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Linagliptin Protects Human SH-SY5Y Neuroblastoma Cells against Amyloid-β Cytotoxicity via the Activation of Wnt1 and Suppression of IL-6 Release
BACKGROUND: Alzheimer’s disease is one of the neurodegenerative disorders typified by the aggregate of Aβ and phosphorylated tau protein. Oxidative stress and neuroinflammation, because of Aβ peptides, are strongly involved in the pathophysiology of AD. Linagliptin shows neuroprotective properties a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pasteur Institute of Iran
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487681/ https://www.ncbi.nlm.nih.gov/pubmed/34425652 http://dx.doi.org/10.52547/ibj.25.5.343 |