Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation

Fibrosis promotes the maintenance of atrial fibrillation (AF), making it resistant to therapy. Improved understanding of the molecular mechanisms leading to atrial fibrosis will open new pathways toward effective antifibrotic therapies. OBJECTIVE: This study aims to decipher the mechanistic interpla...

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Detalles Bibliográficos
Autores principales: Künzel, Stephan R., Hoffmann, Maximilian, Weber, Silvio, Künzel, Karolina, Kämmerer, Susanne, Günscht, Mario, Klapproth, Erik, Rausch, Johanna S.E., Sadek, Mirna S., Kolanowski, Tomasz, Meyer-Roxlau, Stefanie, Piorkowski, Christopher, Tugtekin, Sems M., Rose-John, Stefan, Yin, Xiaoke, Mayr, Manuel, Kuhlmann, Jan Dominik, Wimberger, Pauline, Grützmann, Konrad, Herzog, Natalie, Küpper, Jan-Heiner, O’Reilly, Molly, Kabir, S. Nashitha, Sommerfeld, Laura C., Guan, Kaomei, Wielockx, Ben, Fabritz, Larissa, Nattel, Stanley, Ravens, Ursula, Dobrev, Dobromir, Wagner, Michael, El-Armouche, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487716/
https://www.ncbi.nlm.nih.gov/pubmed/34433292
http://dx.doi.org/10.1161/CIRCRESAHA.121.319425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487716/
https://www.ncbi.nlm.nih.gov/pubmed/34433292
http://dx.doi.org/10.1161/CIRCRESAHA.121.319425

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