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Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma
Although basal cell carcinoma (BCC) is often managed successfully with surgery, patients with locally advanced BCC (laBCC) or metastatic BCC (mBCC) who are not candidates for surgery or radiotherapy have limited treatment options. Most BCCs result from aberrant Hedgehog pathway activation in keratin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487719/ https://www.ncbi.nlm.nih.gov/pubmed/34611482 http://dx.doi.org/10.18632/oncotarget.28080 |