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Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma

Although basal cell carcinoma (BCC) is often managed successfully with surgery, patients with locally advanced BCC (laBCC) or metastatic BCC (mBCC) who are not candidates for surgery or radiotherapy have limited treatment options. Most BCCs result from aberrant Hedgehog pathway activation in keratin...

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Detalles Bibliográficos
Autores principales:	Doan, Hung Q., Chen, Leon, Nawas, Zeena, Lee, Heng-Huan, Silapunt, Sirunya, Migden, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487719/ https://www.ncbi.nlm.nih.gov/pubmed/34611482 http://dx.doi.org/10.18632/oncotarget.28080

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