Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers

Despite increasingly thorough mechanistic understanding of the dominant genetic drivers of gastrointestinal (GI) tumorigenesis (e.g., Ras/Raf, TP53, etc.), only a small proportion of these molecular alterations are therapeutically actionable. In an attempt to address this therapeutic impasse, our gr...

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Detalles Bibliográficos
Autores principales: Dosch, Austin R., Chatila, Walid K., Ban, Yuguang, Bianchi, Anna, Deshpande, Nilesh U., Silva, Iago De Castro, Merchant, Nipun B., Datta, Jashodeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487722/
https://www.ncbi.nlm.nih.gov/pubmed/34611484
http://dx.doi.org/10.18632/oncotarget.27983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487722/
https://www.ncbi.nlm.nih.gov/pubmed/34611484
http://dx.doi.org/10.18632/oncotarget.27983

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