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Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers
Despite increasingly thorough mechanistic understanding of the dominant genetic drivers of gastrointestinal (GI) tumorigenesis (e.g., Ras/Raf, TP53, etc.), only a small proportion of these molecular alterations are therapeutically actionable. In an attempt to address this therapeutic impasse, our gr...
Autores principales: | Dosch, Austin R., Chatila, Walid K., Ban, Yuguang, Bianchi, Anna, Deshpande, Nilesh U., Silva, Iago De Castro, Merchant, Nipun B., Datta, Jashodeep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487722/ https://www.ncbi.nlm.nih.gov/pubmed/34611484 http://dx.doi.org/10.18632/oncotarget.27983 |
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