Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients

Breast cancer (BC) and colorectal cancer (CRC) are common and show poor survival in advanced stages. Using The Cancer Genome Atlas (TCGA) computational tool cBioPortal, we evaluated overall patient survival in BRCA1 mRNA-low versus -high cohorts (<−1.29 versus >1.05 SD from mean BRCA1 expressi...

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Detalles Bibliográficos
Autores principales: Leaf, Sofia, Carlsen, Lindsey, El-Deiry, Wafik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487727/
https://www.ncbi.nlm.nih.gov/pubmed/34611475
http://dx.doi.org/10.18632/oncotarget.28082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487727/
https://www.ncbi.nlm.nih.gov/pubmed/34611475
http://dx.doi.org/10.18632/oncotarget.28082

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