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Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking
Collagen type IV (Col IV) is a basement membrane protein associated with early blood vessel morphogenesis and is essential for blood vessel stability. Defects in vascular Col IV deposition are the basis of heritable disorders, such as small vessel disease, marked by cerebral hemorrhage and drastical...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487879/ https://www.ncbi.nlm.nih.gov/pubmed/33956260 http://dx.doi.org/10.1007/s10456-021-09791-9 |