Pericyte hypoxia-inducible factor-1 (HIF-1) drives blood-brain barrier disruption and impacts acute ischemic stroke outcome

Pericytes play essential roles in blood-brain barrier integrity and their dysfunction is implicated in neurological disorders such as stroke although the underlying mechanisms remain unknown. Hypoxia-inducible factor-1 (HIF-1), a master regulator of injury responses, has divergent roles in different...

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Detalles Bibliográficos
Autores principales: Tsao, Chih-Chieh, Baumann, Julia, Huang, Sheng-Fu, Kindler, Diana, Schroeter, Aileen, Kachappilly, Nicole, Gassmann, Max, Rudin, Markus, Ogunshola, Omolara O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487886/
https://www.ncbi.nlm.nih.gov/pubmed/34046769
http://dx.doi.org/10.1007/s10456-021-09796-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487886/
https://www.ncbi.nlm.nih.gov/pubmed/34046769
http://dx.doi.org/10.1007/s10456-021-09796-4

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