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Going beyond Polycomb: EZH2 Functions in Prostate Cancer

The Polycomb group (PcG) protein Enhancer of Zeste Homolog 2 (EZH2) is one of the three core subunits of the Polycomb Repressive Complex 2 (PRC2). It harbors histone methyltransferase activity (MTase) that specifically catalyze histone 3 lysine 27 (H3K27) methylation on target gene promoters. As suc...

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Detalles Bibliográficos
Autores principales: Park, Su H., Fong, Ka-Wing, Mong, Ezinne, Martin, M. Cynthia, Schiltz, Gary E., Yu, Jindan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487936/
https://www.ncbi.nlm.nih.gov/pubmed/34349243
http://dx.doi.org/10.1038/s41388-021-01982-4