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PPARβ/δ Is Required for Mesenchymal Stem Cell Cardioprotective Effects Independently of Their Anti-inflammatory Properties in Myocardial Ischemia-Reperfusion Injury

Myocardial infarction ranks first for the mortality worldwide. Because the adult heart is unable to regenerate, fibrosis develops to compensate for the loss of contractile tissue after infarction, leading to cardiac remodeling and heart failure. Adult mesenchymal stem cells (MSC) regenerative proper...

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Detalles Bibliográficos
Autores principales: Nernpermpisooth, Nitirut, Sarre, Charlotte, Barrere, Christian, Contreras, Rafaël, Luz-Crawford, Patricia, Tejedor, Gautier, Vincent, Anne, Piot, Christophe, Kumphune, Sarawut, Nargeot, Joel, Jorgensen, Christian, Barrère-Lemaire, Stéphanie, Djouad, Farida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488150/
https://www.ncbi.nlm.nih.gov/pubmed/34616778
http://dx.doi.org/10.3389/fcvm.2021.681002