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Pan-Cancer Analysis Reveals That E1A Binding Protein p300 Mutations Increase Genome Instability and Antitumor Immunity

E1A binding protein p300 (EP300) is mutated in diverse cancers. Nevertheless, a systematic investigation into the associations of EP300 mutations with genome instability and antitumor immunity in pan-cancer remains lacking. Using the datasets from The Cancer Genome Atlas, we analyzed the correlation...

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Detalles Bibliográficos
Autores principales: Chen, Zuobing, Chen, Canping, Li, Lin, Zhang, Tianfang, Wang, Xiaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488206/
https://www.ncbi.nlm.nih.gov/pubmed/34616736
http://dx.doi.org/10.3389/fcell.2021.729927