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Mechanistic Modeling of Maternal Lymphoid and Fetal Plasma Antiretroviral Exposure During the Third Trimester

Pregnancy-induced changes in plasma pharmacokinetics of many antiretrovirals (ARV) are well-established. Current knowledge about the extent of ARV exposure in lymphoid tissues of pregnant women and within the fetal compartment is limited due to their inaccessibility. Subtherapeutic ARV concentration...

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Detalles Bibliográficos
Autores principales: Shenkoya, Babajide, Atoyebi, Shakir, Eniayewu, Ibrahim, Akinloye, Abdulafeez, Olagunju, Adeniyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488224/
https://www.ncbi.nlm.nih.gov/pubmed/34616699
http://dx.doi.org/10.3389/fped.2021.734122