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Interleukin-17A Drives IL-19 and IL-24 Expression in Skin Stromal Cells Regulating Keratinocyte Proliferation

IL-17A has been shown to be up-regulated in psoriasis lesions and is central to psoriasis pathogenesis. IL-19, along with other IL-20 subfamily cytokines such as IL-20 and IL-24, is induced by IL-17A and contributes especially to epidermal hyperplasia in psoriasis. However, the regulation, cellular...

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Detalles Bibliográficos
Autores principales: Xu, Xiaofei, Prens, Errol, Florencia, Edwin, Leenen, Pieter, Boon, Luis, Asmawidjaja, Patrick, Mus, Anne-Marie, Lubberts, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488340/
https://www.ncbi.nlm.nih.gov/pubmed/34616394
http://dx.doi.org/10.3389/fimmu.2021.719562