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MAT2A-Mediated S-Adenosylmethionine Level in CD4(+) T Cells Regulates HIV-1 Latent Infection

Antiretroviral drugs effectively halt HIV-1 replication and disease progression, however, due to the presence of a stable viral latent reservoir, the infection cannot be cured by antiretroviral drugs alone. Elucidating the molecular mechanisms underlying HIV-1 latent infection remains a critical hur...

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Detalles Bibliográficos
Autores principales: Yang, Xiaofan, Huang, Ting, Wang, Tiantian, Gao, Hongbo, Zhang, Haitao, Peng, Wen, Zhao, Jiacong, Hu, Shujing, Lu, Panpan, Hong, Zhongsi, Li, Bo, Deng, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488394/
https://www.ncbi.nlm.nih.gov/pubmed/34616406
http://dx.doi.org/10.3389/fimmu.2021.745784