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Coxiella burnetii Whole Cell Vaccine Produces a Th1 Delayed-Type Hypersensitivity Response in a Novel Sensitized Mouse Model

Q-VAX®, a whole cell, formalin-inactivated vaccine, is the only vaccine licensed for human use to protect against Coxiella burnetii, the cause of Q fever. Although this vaccine provides long-term protection, local and systemic reactogenic responses are common in previously sensitized individuals whi...

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Detalles Bibliográficos
Autores principales: Fratzke, Alycia P., Gregory, Anthony E., van Schaik, Erin J., Samuel, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488435/
https://www.ncbi.nlm.nih.gov/pubmed/34616410
http://dx.doi.org/10.3389/fimmu.2021.754712