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Weighted Gene Co-Expression Network Analysis Identifies ANGPTL4 as a Key Regulator in Diabetic Cardiomyopathy via FAK/SIRT3/ROS Pathway in Cardiomyocyte

BACKGROUND: Diabetic cardiomyopathy (DbCM) is characterized by initial impairment of left ventricular relaxation followed by contractile dysfunction. Despite intensive research, the exact mechanism remains so far unsolved. METHODS: We constructed weighted gene co-expression network analysis (WGCNA)...

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Detalles Bibliográficos
Autores principales: Dai, Lei, Xie, Yang, Zhang, Wenjun, Zhong, Xiaodan, Wang, Mengwen, Jiang, Hongcheng, He, Zhen, Liu, Xiaolei, Zeng, Hesong, Wang, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488438/
https://www.ncbi.nlm.nih.gov/pubmed/34616362
http://dx.doi.org/10.3389/fendo.2021.705154