Engineering of fully humanized and vascularized 3D bone marrow niches sustaining undifferentiated human cord blood hematopoietic stem and progenitor cells

Hematopoietic stem and progenitor cells (HSPCs) are frequently located around the bone marrow (BM) vasculature. These so-called perivascular niches regulate HSC function both in health and disease, but they have been poorly studied in humans due to the scarcity of models integrating complete human v...

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Detalles Bibliográficos
Autores principales: Born, Gordian, Nikolova, Marina, Scherberich, Arnaud, Treutlein, Barbara, García-García, Andrés, Martin, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488506/
https://www.ncbi.nlm.nih.gov/pubmed/34616539
http://dx.doi.org/10.1177/20417314211044855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488506/
https://www.ncbi.nlm.nih.gov/pubmed/34616539
http://dx.doi.org/10.1177/20417314211044855

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