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Fluc‐EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease

The cellular protein quality control machinery is important for preventing protein misfolding and aggregation. Declining protein homeostasis (proteostasis) is believed to play a crucial role in age‐related neurodegenerative disorders. However, how neuronal proteostasis capacity changes in different...

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Detalles Bibliográficos
Autores principales: Blumenstock, Sonja, Schulz‐Trieglaff, Elena Katharina, Voelkl, Kerstin, Bolender, Anna‐Lena, Lapios, Paul, Lindner, Jana, Hipp, Mark S, Hartl, F Ulrich, Klein, Rüdiger, Dudanova, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488555/
https://www.ncbi.nlm.nih.gov/pubmed/34410010
http://dx.doi.org/10.15252/embj.2020107260