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Fluc‐EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease
The cellular protein quality control machinery is important for preventing protein misfolding and aggregation. Declining protein homeostasis (proteostasis) is believed to play a crucial role in age‐related neurodegenerative disorders. However, how neuronal proteostasis capacity changes in different...
Autores principales: | Blumenstock, Sonja, Schulz‐Trieglaff, Elena Katharina, Voelkl, Kerstin, Bolender, Anna‐Lena, Lapios, Paul, Lindner, Jana, Hipp, Mark S, Hartl, F Ulrich, Klein, Rüdiger, Dudanova, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488555/ https://www.ncbi.nlm.nih.gov/pubmed/34410010 http://dx.doi.org/10.15252/embj.2020107260 |
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