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Role of the CCL2‐CCR2 signalling axis in cancer: Mechanisms and therapeutic targeting

The chemokine ligand CCL2 and its receptor CCR2 are implicated in the initiation and progression of various cancers. CCL2 can activate tumour cell growth and proliferation through a variety of mechanisms. By interacting with CCR2, CCL2 promotes cancer cell migration and recruits immunosuppressive ce...

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Detalles Bibliográficos
Autores principales: Xu, Maosen, Wang, Yang, Xia, Ruolan, Wei, Yuquan, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488570/
https://www.ncbi.nlm.nih.gov/pubmed/34464477
http://dx.doi.org/10.1111/cpr.13115