Cargando…

Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling

T cell activation is initiated by T cell receptor (TCR) phosphorylation. This requires the local depletion of large receptor-type phosphatases from “close contacts” formed when T cells interact with surfaces presenting agonistic TCR ligands, but exactly how the ligands potentiate signaling is unclea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Kevin Y., Jenkins, Edward, Körbel, Markus, Ponjavic, Aleks, Lippert, Anna H., Santos, Ana Mafalda, Ashman, Nicole, O'Brien-Ball, Caitlin, McBride, Jemma, Klenerman, David, Davis, Simon J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488633/ https://www.ncbi.nlm.nih.gov/pubmed/34526387 http://dx.doi.org/10.1073/pnas.2024250118

Ejemplares similares

The Costs of Close Contacts: Visualizing the Energy Landscape of Cell Contacts at the Nanoscale
por: Kulenkampff, Klara, et al.
Publicado: (2020)

Antigen discrimination by T cells relies on size-constrained microvillar contact
por: Jenkins, Edward, et al.
Publicado: (2023)

Three-Dimensional Super-Resolution in Eukaryotic Cells Using the Double-Helix Point Spread Function
por: Carr, Alexander R., et al.
Publicado: (2017)

Sensitive light-sheet microscopy in multiwell plates using an AFM cantilever
por: Ponjavic, Aleks, et al.
Publicado: (2018)

4D imaging reveals stage dependent random and directed cell motion during somite morphogenesis
por: McColl, James, et al.
Publicado: (2018)

Single-Molecule Imaging of Wnt3A Protein Diffusion on Living Cell Membranes
por: Lippert, Anna, et al.
Publicado: (2017)

Single-molecule visualisation of DNA G-quadruplex formation in live cells
por: Di Antonio, Marco, et al.
Publicado: (2020)

Initiation of T cell signaling by CD45 segregation at ‘close-contacts’
por: Chang, Veronica T, et al.
Publicado: (2016)

A cell topography-based mechanism for ligand discrimination by the T cell receptor
por: Fernandes, Ricardo A., et al.
Publicado: (2019)

Understanding immune signaling using advanced imaging techniques
por: Brameshuber, Mario, et al.
Publicado: (2022)

Direct Observation of Murine Prion Protein Replication in Vitro
por: Sang, Jason C., et al.
Publicado: (2018)

resPAINT: Accelerating Volumetric Super‐Resolution Localisation Microscopy by Active Control of Probe Emission
por: Sanders, Edward W., et al.
Publicado: (2022)

Reconstitution of immune cell interactions in free-standing membranes
por: Jenkins, Edward, et al.
Publicado: (2019)

Fast extraction at slow extaction momenta for trapping of Antiprotons
por: Baird, S
Publicado: (1987)

Fast extraction at slow extraction momenta for trapping of antiprotons
por: Baird, S A
Publicado: (1988)

Mechanical Behavior of Stainless Steel Fiber-Reinforced Composites Exposed to Accelerated Corrosion
por: O’Brien, Caitlin, et al.
Publicado: (2017)

Ultrafast Charge Dynamics in Trap‐Free and Surface‐Trapping Colloidal Quantum Dots
por: Smith, Charles T., et al.
Publicado: (2015)

Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
por: Sušac, Lukas, et al.
Publicado: (2022)

Tornado type closed magnetic trap for an ECR source
por: Abramova, K B, et al.
Publicado: (1999)

The advantage of being slow: The quasi-neutral contact process
por: de Oliveira, Marcelo Martins, et al.
Publicado: (2017)

Voltage-dependent slowing of K channel closing kinetics by Rb+
Publicado: (1991)

Cooperative Stabilization of Close-Contact Zones Leads to Sensitivity and Selectivity in T-Cell Recognition
por: Różycki, Bartosz, et al.
Publicado: (2021)

A microfluidic platform for trapping, releasing and super-resolution imaging of single cells
por: Zhou, Ying, et al.
Publicado: (2016)

To close or not to close? Analysis of 4 year's data from national surveillance of norovirus outbreaks in hospitals in England
por: Harris, John P, et al.
Publicado: (2014)

Single-cell measurements of two-dimensional binding affinity across cell contacts
por: Chouliara, Manto, et al.
Publicado: (2021)

Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping
por: Bongiovanni, Marie N., et al.
Publicado: (2016)

Close Encounters of the Cell Kind: The Impact of Contact Inhibition on Tumour Growth and Cancer Models
por: Grimes, David Robert, et al.
Publicado: (2020)

Description of closed loop control system for slow ejection (Servo-spill)
por: Shering, G, et al.
Publicado: (1968)

Numbers of close contacts of individuals infected with SARS-CoV-2 and their association with government intervention strategies
por: McAloon, Conor G., et al.
Publicado: (2021)

A Trapped Intracellular Cation Modulates K(+) Channel Recovery From Slow Inactivation
por: Ray, Evan C., et al.
Publicado: (2006)

Trapping of Organic Blockers by Closing of Voltage-dependent K(+) Channels : Evidence for a Trap Door Mechanism of Activation Gating
por: Holmgren, Miguel, et al.
Publicado: (1997)

Whisker Contact Detection of Rodents Based on Slow and Fast Mechanical Inputs
por: Claverie, Laure N., et al.
Publicado: (2017)

Mixing patterns and the spread of close-contact infectious diseases
por: Edmunds, WJ, et al.
Publicado: (2006)

Closing open contacts adjacent to an implant-supported restoration
por: Liu, Xiaoqiang, et al.
Publicado: (2019)

Closing the Gap: Membrane Contact Sites in the Regulation of Autophagy
por: Kohler, Verena, et al.
Publicado: (2020)

Coronaviruses Detected in Bats in Close Contact with Humans in Rwanda
por: Nziza, Julius, et al.
Publicado: (2019)

Probable close contact transmission in a restaurant in China
por: Zhang, Nan, et al.
Publicado: (2022)

A large close relative of C. elegans is slow-developing but not long-lived
por: Woodruff, Gavin C., et al.
Publicado: (2019)

Susceptibility to auditory closed-loop stimulation of sleep slow oscillations changes with age
por: Schneider, Jules, et al.
Publicado: (2020)

An Open Standard for Camera Trap Data
por: Forrester, Tavis, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2afntarj496juisgqck567tss6