Distinct single-component adjuvants steer human DC-mediated T-cell polarization via Toll-like receptor signaling toward a potent antiviral immune response

The COVID-19 pandemic highlights the importance of efficient and safe vaccine development. Vaccine adjuvants are essential to boost and tailor the immune response to the corresponding pathogen. To allow for an educated selection, we assessed the effect of different adjuvants on human monocyte-derive...

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Detalles Bibliográficos
Autores principales: Roßmann, Laura, Bagola, Katrin, Stephen, Tharshana, Gerards, Anna-Lisa, Walber, Bianca, Ullrich, Anja, Schülke, Stefan, Kamp, Christel, Spreitzer, Ingo, Hasan, Milena, David-Watine, Brigitte, Shorte, Spencer L., Bastian, Max, van Zandbergen, Ger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488681/
https://www.ncbi.nlm.nih.gov/pubmed/34561306
http://dx.doi.org/10.1073/pnas.2103651118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488681/
https://www.ncbi.nlm.nih.gov/pubmed/34561306
http://dx.doi.org/10.1073/pnas.2103651118

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