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Distinct single-component adjuvants steer human DC-mediated T-cell polarization via Toll-like receptor signaling toward a potent antiviral immune response
The COVID-19 pandemic highlights the importance of efficient and safe vaccine development. Vaccine adjuvants are essential to boost and tailor the immune response to the corresponding pathogen. To allow for an educated selection, we assessed the effect of different adjuvants on human monocyte-derive...
Autores principales: | Roßmann, Laura, Bagola, Katrin, Stephen, Tharshana, Gerards, Anna-Lisa, Walber, Bianca, Ullrich, Anja, Schülke, Stefan, Kamp, Christel, Spreitzer, Ingo, Hasan, Milena, David-Watine, Brigitte, Shorte, Spencer L., Bastian, Max, van Zandbergen, Ger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488681/ https://www.ncbi.nlm.nih.gov/pubmed/34561306 http://dx.doi.org/10.1073/pnas.2103651118 |
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