The ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis through modulation of P2X4 receptor–dependent metabolism in myeloid cells

Extracellular adenosine triphosphate (ATP) released by mucosal immune cells and by microbiota in the intestinal lumen elicits diverse immune responses that mediate the intestinal homeostasis via P2 purinergic receptors, while overactivation of ATP signaling leads to mucosal immune system disruption,...

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Detalles Bibliográficos
Autores principales: Tani, Haruka, Li, Bo, Kusu, Takashi, Okumura, Ryu, Nishimura, Junichi, Okuzaki, Daisuke, Motooka, Daisuke, Arakawa, Shoya, Mori, Asuka, Yoshihara, Terukazu, Ogino, Takayuki, Tsai, Shih-Han, Furuta, Yoki, Muneta, Masato, Nakamura, Shota, Fukusaki, Eiichiro, Yamamoto, Kimiko, Yagita, Hideo, Kayama, Hisako, Takeda, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488689/
https://www.ncbi.nlm.nih.gov/pubmed/34548395
http://dx.doi.org/10.1073/pnas.2100594118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488689/
https://www.ncbi.nlm.nih.gov/pubmed/34548395
http://dx.doi.org/10.1073/pnas.2100594118

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