Eliciting an immune-mediated antitumor response through oncolytic herpes simplex virus-based shared antigen expression in tumors resistant to viroimmunotherapy

BACKGROUND: Oncolytic virotherapy (OV) is an immunotherapy that incorporates viral cancer cell lysis with engagement of the recruited immune response against cancer cells. Pediatric solid tumors are challenging targets because they contain both an inert immune environment and a quiet antigenic lands...

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Detalles Bibliográficos
Autores principales: Ghonime, Mohammed G, Saini, Uksha, Kelly, Michael C, Roth, Justin C, Wang, Pin-Yi, Chen, Chun-Yu, Miller, Katherine, Hernandez-Aguirre, Ilse, Kim, Yeaseul, Mo, Xiaokui, Stanek, Joseph R, Cripe, Tim, Mardis, Elaine, Cassady, Kevin A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488720/
https://www.ncbi.nlm.nih.gov/pubmed/34599026
http://dx.doi.org/10.1136/jitc-2021-002939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488720/
https://www.ncbi.nlm.nih.gov/pubmed/34599026
http://dx.doi.org/10.1136/jitc-2021-002939

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