Bispecific antibody targeting TROP2xCD3 suppresses tumor growth of triple negative breast cancer

BACKGROUND: Triple negative breast cancer (TNBC) is a subtype of breast cancers with poor prognosis and targeted drug therapies are limited. To develop novel and efficacious therapies for TNBC, we developed a bispecific antibody F7AK3 that recognizes both trophoblast cell surface antigen 2 (TROP2) a...

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Detalles Bibliográficos
Autores principales: Liu, Huicheng, Bai, Lili, Huang, Liu, Ning, Na, Li, Lin, Li, Yijia, Dong, Xuejiao, Du, Qiuyang, Xia, Minghui, Chen, Yufei, Zhao, Likun, Li, Yanhu, Meng, Qingwu, Wang, Jing, Duan, Yaqi, Ming, Jie, Yuan, Andy Qingan, Yang, Xiang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488747/
https://www.ncbi.nlm.nih.gov/pubmed/34599021
http://dx.doi.org/10.1136/jitc-2021-003468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488747/
https://www.ncbi.nlm.nih.gov/pubmed/34599021
http://dx.doi.org/10.1136/jitc-2021-003468

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