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One‐Step Polymerase Chain Reaction‐Free Nanowire‐Based Plasma Cell‐Free DNA Assay to Detect EML4‐ALK Fusion and to Monitor Resistance in Lung Cancer

BACKGROUND: Next‐generation sequencing has mostly been used for genotyping cell‐free DNA (cfDNA) in plasma. However, this assay has several clinical limitations. We evaluated the clinical utility of a novel polymerase chain reaction–free nanowire (NW)‐based plasma cfDNA assay for detecting ALK fusio...

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Detalles Bibliográficos
Autores principales: Lee, Youngjoo, Cho, Youngnam, Park, Eun Young, Park, Seong‐Yun, Hwang, Kum Hui, Han, Ji‐Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488792/
https://www.ncbi.nlm.nih.gov/pubmed/34272914
http://dx.doi.org/10.1002/onco.13902