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Glypican 4 mediates Wnt transport between germ layers via signaling filopodia

Glypicans influence signaling pathways by regulating morphogen trafficking and reception. However, the underlying mechanisms in vertebrates are poorly understood. In zebrafish, Glypican 4 (Gpc4) is required for convergence and extension (C&E) of both the mesoderm and endoderm. Here, we show that...

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Detalles Bibliográficos
Autores principales: Hu, Bo, Rodriguez, Juan J., Kakkerla Balaraju, Anurag, Gao, Yuanyuan, Nguyen, Nhan T., Steen, Heston, Suhaib, Saeb, Chen, Songhai, Lin, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488972/
https://www.ncbi.nlm.nih.gov/pubmed/34591076
http://dx.doi.org/10.1083/jcb.202009082