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Glypican 4 mediates Wnt transport between germ layers via signaling filopodia
Glypicans influence signaling pathways by regulating morphogen trafficking and reception. However, the underlying mechanisms in vertebrates are poorly understood. In zebrafish, Glypican 4 (Gpc4) is required for convergence and extension (C&E) of both the mesoderm and endoderm. Here, we show that...
Autores principales: | Hu, Bo, Rodriguez, Juan J., Kakkerla Balaraju, Anurag, Gao, Yuanyuan, Nguyen, Nhan T., Steen, Heston, Suhaib, Saeb, Chen, Songhai, Lin, Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488972/ https://www.ncbi.nlm.nih.gov/pubmed/34591076 http://dx.doi.org/10.1083/jcb.202009082 |
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