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Engineering chromosome rearrangements in cancer

The identification of large chromosomal rearrangements in cancers has multiplied exponentially over the last decade. These complex and often rare genomic events have traditionally been challenging to study, in part owing to lack of tools that efficiently engineer disease-associated inversions, delet...

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Detalles Bibliográficos
Autores principales: Alonso, Salvador, Dow, Lukas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489016/
https://www.ncbi.nlm.nih.gov/pubmed/34585724
http://dx.doi.org/10.1242/dmm.049078