Transforming growth factor β3 deficiency promotes defective lipid metabolism and fibrosis in murine kidney

Glomerulosclerosis and tubulointerstitial fibrosis are pathological features of chronic kidney disease. Transforming growth factor β (TGFβ) is a key player in the development of fibrosis. However, of the three known TGFβ isoforms, only TGFβ1 has an established role in fibrosis, and the pathophysiolo...

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Detalles Bibliográficos
Autores principales: Escasany, Elia, Lanzón, Borja, García-Carrasco, Almudena, Izquierdo-Lahuerta, Adriana, Torres, Lucía, Corrales, Patricia, Rodríguez Rodríguez, Ana Elena, Luis-Lima, Sergio, Martínez Álvarez, Concepción, Javier Ruperez, Francisco, Ros, Manuel, Porrini, Esteban, Rydén, Mikael, Medina-Gómez, Gema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489029/
https://www.ncbi.nlm.nih.gov/pubmed/34431499
http://dx.doi.org/10.1242/dmm.048249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489029/
https://www.ncbi.nlm.nih.gov/pubmed/34431499
http://dx.doi.org/10.1242/dmm.048249

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