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Transforming growth factor β3 deficiency promotes defective lipid metabolism and fibrosis in murine kidney
Glomerulosclerosis and tubulointerstitial fibrosis are pathological features of chronic kidney disease. Transforming growth factor β (TGFβ) is a key player in the development of fibrosis. However, of the three known TGFβ isoforms, only TGFβ1 has an established role in fibrosis, and the pathophysiolo...
Autores principales: | Escasany, Elia, Lanzón, Borja, García-Carrasco, Almudena, Izquierdo-Lahuerta, Adriana, Torres, Lucía, Corrales, Patricia, Rodríguez Rodríguez, Ana Elena, Luis-Lima, Sergio, Martínez Álvarez, Concepción, Javier Ruperez, Francisco, Ros, Manuel, Porrini, Esteban, Rydén, Mikael, Medina-Gómez, Gema |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489029/ https://www.ncbi.nlm.nih.gov/pubmed/34431499 http://dx.doi.org/10.1242/dmm.048249 |
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