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Practical identifiability in the frame of nonlinear mixed effects models: the example of the in vitro erythropoiesis

BACKGROUND: Nonlinear mixed effects models provide a way to mathematically describe experimental data involving a lot of inter-individual heterogeneity. In order to assess their practical identifiability and estimate confidence intervals for their parameters, most mixed effects modelling programs us...

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Detalles Bibliográficos
Autores principales: Duchesne, Ronan, Guillemin, Anissa, Gandrillon, Olivier, Crauste, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489053/
https://www.ncbi.nlm.nih.gov/pubmed/34607573
http://dx.doi.org/10.1186/s12859-021-04373-4