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Identification, visualization, statistical analysis and mathematical modeling of high-feedback loops in gene regulatory networks

BACKGROUND: Feedback loops in gene regulatory networks play pivotal roles in governing functional dynamics of cells. Systems approaches demonstrated characteristic dynamical features, including multistability and oscillation, of positive and negative feedback loops. Recent experiments and theories h...

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Detalles Bibliográficos
Autores principales: Nordick, Benjamin, Hong, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489061/
https://www.ncbi.nlm.nih.gov/pubmed/34607562
http://dx.doi.org/10.1186/s12859-021-04405-z