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Identification, visualization, statistical analysis and mathematical modeling of high-feedback loops in gene regulatory networks
BACKGROUND: Feedback loops in gene regulatory networks play pivotal roles in governing functional dynamics of cells. Systems approaches demonstrated characteristic dynamical features, including multistability and oscillation, of positive and negative feedback loops. Recent experiments and theories h...
Autores principales: | Nordick, Benjamin, Hong, Tian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489061/ https://www.ncbi.nlm.nih.gov/pubmed/34607562 http://dx.doi.org/10.1186/s12859-021-04405-z |
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