Metformin and arsenic trioxide synergize to trigger Parkin/pink1-dependent mitophagic cell death in human cervical cancer HeLa cells

Mitochondria are involved in various biological processes including intracellular homeostasis, proliferation, senescence, and death, and mitochondrial mitophagy is closely related to the development and regression of malignant tumors. Recent studies confirmed that the hypoglycemic drug metformin (Me...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Zhou, Cunmin, Yi, Juan, Sun, Jingjing, Xie, Bei, Zhang, Zhewen, Wang, Qunfeng, Chen, Gang, Jin, Suya, Hou, Jinxia, Qin, Miao, Wang, Lina, Wei, Hulai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489132/
https://www.ncbi.nlm.nih.gov/pubmed/34659521
http://dx.doi.org/10.7150/jca.61299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489132/
https://www.ncbi.nlm.nih.gov/pubmed/34659521
http://dx.doi.org/10.7150/jca.61299

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