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Metformin and arsenic trioxide synergize to trigger Parkin/pink1-dependent mitophagic cell death in human cervical cancer HeLa cells
Mitochondria are involved in various biological processes including intracellular homeostasis, proliferation, senescence, and death, and mitochondrial mitophagy is closely related to the development and regression of malignant tumors. Recent studies confirmed that the hypoglycemic drug metformin (Me...
Autores principales: | Chen, Jing, Zhou, Cunmin, Yi, Juan, Sun, Jingjing, Xie, Bei, Zhang, Zhewen, Wang, Qunfeng, Chen, Gang, Jin, Suya, Hou, Jinxia, Qin, Miao, Wang, Lina, Wei, Hulai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489132/ https://www.ncbi.nlm.nih.gov/pubmed/34659521 http://dx.doi.org/10.7150/jca.61299 |
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