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Suppressing LncRNA HOXA-AS3 by CRISPR-dCas9 inhibits pancreatic cancer development

The lncRNA HOXA-AS3 has been reported as a potential oncogene in tumors. Nevertheless, the molecular mechanism of HOXA-AS3 in pancreatic cancer (PC) progression remains unknown. We performed quantitative real-time (qRT) PCR assay to detect the expression levels of HOXA-AS3, miR-29c in PC specimens....

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoli, Zhu, Hongbo, Qu, Xiaoguang, Yu, Ziying, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489150/
https://www.ncbi.nlm.nih.gov/pubmed/34659534
http://dx.doi.org/10.7150/jca.62631