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Gangrene, revascularization, and limb function improved with E-selectin/adeno-associated virus gene therapy

OBJECTIVE: Novel therapeutic angiogenic concepts for critical limb ischemia are still needed for limb salvage. E-selectin, a cell-adhesion molecule, is vital for recruitment of the stem/progenitor cells necessary for neovascularization in ischemic tissues. We hypothesized that priming ischemic limb...

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Detalles Bibliográficos
Autores principales: Quiroz, Hallie J., Parikh, Punam P., Lassance-Soares, Roberta M., Regueiro, Manuela M., Li, Yan, Shao, Hongwei, Vazquez-Padron, Roberto, Percival, Justin, Liu, Zhao-Jun, Velazquez, Omaida C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489216/
https://www.ncbi.nlm.nih.gov/pubmed/34617055
http://dx.doi.org/10.1016/j.jvssci.2020.10.001