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Targeting smooth muscle cell phenotypic switching in vascular disease

OBJECTIVE: The phenotypic plasticity of vascular smooth muscle cells (VSMCs) is central to vessel growth and remodeling, but also contributes to cardiovascular pathologies. New technologies including fate mapping, single cell transcriptomics, and genetic and pharmacologic inhibitors have provided fu...

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Detalles Bibliográficos
Autores principales: Chakraborty, Raja, Chatterjee, Payel, Dave, Jui M., Ostriker, Allison C., Greif, Daniel M., Rzucidlo, Eva M., Martin, Kathleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489222/
https://www.ncbi.nlm.nih.gov/pubmed/34617061
http://dx.doi.org/10.1016/j.jvssci.2021.04.001