Increased matrix metalloproteinase 9 activity correlates with flow-mediated intraluminal thrombus deposition and wall degeneration in human abdominal aortic aneurysm

OBJECTIVE: We have previously demonstrated that human abdominal aortic aneurysm (AAA) rupture occurs in zones of low wall shear stress where flow recirculation and intraluminal thrombus (ILT) deposition are increased. Matrix metalloproteinase-9 (MMP-9) is involved in the pathogenesis of AAA via its...

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Detalles Bibliográficos
Autores principales: Ducas, Annie A., Kuhn, David C.S., Bath, Lauren C., Lozowy, Richard J., Boyd, April J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Basic Reserch Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489223/
https://www.ncbi.nlm.nih.gov/pubmed/34617048
http://dx.doi.org/10.1016/j.jvssci.2020.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489223/
https://www.ncbi.nlm.nih.gov/pubmed/34617048
http://dx.doi.org/10.1016/j.jvssci.2020.09.004

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