Xanthohumol Inhibited Mechanical Stimulation-Induced Articular ECM Degradation by Mediating lncRNA GAS5/miR-27a Axis

Osteoarthritis (OA) is histopathologically marked by extracellular matrix (ECM) degradation in joint cartilage. Abnormal mechanical stimulation on joint cartilage may result in ECM degeneration and OA development. Matrix metalloproteinase 13 (MMP-13) is one of the catabolic enzymes contributing to t...

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Detalles Bibliográficos
Autores principales: Zheng, Tiansheng, Zhou, Qingluo, Huang, Jishang, Lai, Jinliang, Ji, Guanglin, Kong, Dechao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489376/
https://www.ncbi.nlm.nih.gov/pubmed/34616299
http://dx.doi.org/10.3389/fphar.2021.737552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489376/
https://www.ncbi.nlm.nih.gov/pubmed/34616299
http://dx.doi.org/10.3389/fphar.2021.737552

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