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Polycomb group proteins in cancer: multifaceted functions and strategies for modulation

Polycomb repressive complexes (PRCs) are a heterogenous collection of dozens, if not hundreds, of protein complexes composed of various combinations of subunits. PRCs are transcriptional repressors important for cell-type specificity during development, and as such, are commonly mis-regulated in can...

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Detalles Bibliográficos
Autores principales: Wang, Sijie, C. Ordonez-Rubiano, Sandra, Dhiman, Alisha, Jiao, Guanming, Strohmier, Brayden P, Krusemark, Casey J, Dykhuizen, Emily C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489530/
https://www.ncbi.nlm.nih.gov/pubmed/34617019
http://dx.doi.org/10.1093/narcan/zcab039