Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques

The speed of development, versatility and efficacy of mRNA-based vaccines have been amply demonstrated in the case of SARS-CoV-2. DNA vaccines represent an important alternative since they induce both humoral and cellular immune responses in animal models and in human trials. We tested the immunogen...

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Detalles Bibliográficos
Autores principales: Rosati, Margherita, Agarwal, Mahesh, Hu, Xintao, Devasundaram, Santhi, Stellas, Dimitris, Chowdhury, Bhabadeb, Bear, Jenifer, Burns, Robert, Donohue, Duncan, Pessaint, Laurent, Andersen, Hanne, Lewis, Mark G., Terpos, Evangelos, Dimopoulos, Meletios Athanasios, Wlodawer, Alexander, Mullins, James I., Venzon, David J., Pavlakis, George N., Felber, Barbara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489704/
https://www.ncbi.nlm.nih.gov/pubmed/34551020
http://dx.doi.org/10.1371/journal.ppat.1009701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489704/
https://www.ncbi.nlm.nih.gov/pubmed/34551020
http://dx.doi.org/10.1371/journal.ppat.1009701

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