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Abnormal Dihydropyrimidine Dehydrogenase Activity as an Indicator of Potential 5-Fluorouracil Linked Cardiotoxicity in Colorectal Cancer Patients: Are Toxic Events Inevitable?

Colorectal cancer (CRC) treatment can be limited to surgical resection for low stages of the disease while subsequent chemotherapy is the preferred treatment for the higher-stage disease. This chemotherapy relies heavily on fluoropyrimidine: 5-fluorouracil (5-FU) and capecitabine, a role played for...

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Detalles Bibliográficos
Autores principales: Chakwop Ngassa, Hyginus, Elmenawi, Khaled A, Anil, Vishwanath, Gosal, Harpreet, Kaur, Harsimran, Mohammed, Lubna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489794/
https://www.ncbi.nlm.nih.gov/pubmed/34650886
http://dx.doi.org/10.7759/cureus.17712